Hydroxyl Magnetic beads (200 nm, 10 mg/mL) are characterized by superparamagnetism, fast magnetic response, abundant hydroxyl functional groups, monodispersity, and submicron scale particle size, which are able to specifically bind to nucleic acids in solution through hydrophobic, hydrogen-bonding, and electrostatic interactions under high salt and low pH conditions, and can rapidly isolate nucleic acids from biological samples, which is conducive to the automation and high throughput extraction of nucleic acids.
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